Article
Treatment and survival of patients with EGFR-mutated non-small cell lung cancer and leptomeningeal metastasis: A retrospective cohort analysis.
Lung cancer (Amsterdam, Netherlands) - 1 Sept 2015
Kuiper Justine L, Hendriks Lizza E, van der Wekken Anthonie J, de Langen Adrianus J, Bahce Idris, Thunnissen Erik, Heideman Daniëlle A M, Berk Yvonne, Buijs Ed J M, Speel Ernst-Jan M, Krouwels Frans H, Smit Hans J M, Groen Harry J M, Dingemans Anne-Marie C, Smit Egbert F
Abstract excerpt
OBJECTIVES: Development of leptomeningeal metastasis (LM) in non-small cell lung cancer (NSCLC)-patients is associated with a poor prognosis. It has been suggested that LM-patients with epidermal growth factor receptor mutated (EGFR+) NSCLC have a superior prognosis compared to EGFR-wild type NSCLC. Studies in EGFR+ NSCLC-patients with LM are scarce. We retrospectively evaluated a multi-institutional cohort of...
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