Article
The prognostic value of TMB and the relationship between TMB and immune infiltration in head and neck squamous cell carcinoma: A gene expression-based study.
Oral oncology - 1 Nov 2020
Zhang Lizao, Li Bowen, Peng Yu, Wu Fan, Li Qunxing, Lin Zhaoyu, Xie Shule, Xiao Liping, Lin Xinyu, Ou Zhanpeng, Cai Tingting, Rong Haixu, Fan Song, Li Jinsong
Abstract excerpt
OBJECTIVE: Whether tumor mutation burden (TMB) affects prognosis and immune infiltration of tumor patients is controversial. We designed and conducted a multi-omics study with the aim of investigating the prognostic value of TMB and the relationship between TMB and immune infiltration in head and neck squamous cell carcinoma (HNSCC). METHODS: TMB scores were calculated from the mutation data of 506 HNSCC samples...
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