Article
Endothelial cell plasticity: how to become and remain a lymphatic endothelial cell
16 Jan 2010
Abstract excerpt
Lineage commitment and differentiation into mature cell types are mostly considered to be unidirectional and irreversible processes. However, recent results have challenged this by showing that terminally differentiated cell types can be reprogrammed into other cell types, an important step towards devising strategies for gene therapy and tissue regeneration. In this Review, we summarize recent data on the...
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