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Article

SMALL ORGAN4 Is a Ribosome Biogenesis Factor Involved in 5.8S Ribosomal RNA Maturation.

Plant physiology - 1 Dec 2020

Micol-Ponce Rosa, Sarmiento-Mañús Raquel, Fontcuberta-Cervera Sara, Cabezas-Fuster Adrián, de Bures Anne, Sáez-Vásquez Julio, Ponce María Rosa

Abstract excerpt

Ribosome biogenesis is crucial for cellular metabolism and has important implications for disease and aging. Human (Homo sapiens) glioma tumor-suppressor candidate region gene2 (GLTSCR2) and yeast (Saccharomyces cerevisiae) Nucleolar protein53 (Nop53) are orthologous proteins with demonstrated roles as ribosome biogenesis factors; knockdown of GLTSCR2 impairs maturation of 18S and 5.8S ribosomal RNAs (rRNAs), and...

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Identifiers

PMID: 32913045
DOI: 10.1104/pp.19.01540
PMCID: PMC7723108

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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