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Article

Q192R polymorphism in the PON1 gene and nasal polyp in a Turkish population.

Journal of biochemical and molecular toxicology - 1 Jan 2021

Solmaz Avcikurt Ayla, Gencer Nahit, Yazici Hasmet

Abstract excerpt

The pathogenesis of nasal polyps is not completely understood. Oxidative damage contributes to polyp formation in the nasal mucosa. The paraoxonase 1 (PON1) enzyme is an important liver enzyme with high antioxidant activity. In this study, we investigated the correlation between Q192R genotypic polymorphism of the PON1 enzyme and nasal-polyp disease. The study examined 62 nasal-polyp patients and 88 controls....

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PMID: 32905659
DOI: 10.1002/jbt.22628

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