Article
Identification of 58 novel HLA alleles identified in Chinese individuals by next-generation sequencing.
HLA - 1 Sept 2023
Cheung Stephen K F, Choi Leo C W, Chan Y S, Ho Jenny C Y, Lee C K, Kwok Janette S Y
Abstract excerpt
HLA genes are the most polymorphic in the human genome. High resolution HLA typing from 13,870 bone marrow donors in Hong Kong was obtained using Next-generation sequencing (NGS) technology. Among the 67 novel alleles identified, official HLA allele names of 50 novel class I alleles (HLA-A, -B, -C) and 8 novel class II alleles (HLA-DRB1, -DQB1) were assigned by the World Health Organization (WHO) Nomenclature...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
