Article
The interaction of Escherichia coli O157 :H7 and Salmonella Typhimurium flagella with host cell membranes and cytoskeletal components.
Microbiology (Reading, England) - 1 Oct 2020
Wolfson Eliza B, Elvidge Johanna, Tahoun Amin, Gillespie Trudi, Mantell Judith, McAteer Sean P, Rossez Yannick, Paxton Edith, Lane Fiona, Shaw Darren J, Gill Andrew C, Stevens Jo, Verkade Paul, Blocker Ariel, Mahajan Arvind, Gally David L
Abstract excerpt
Bacterial flagella have many established roles beyond swimming motility. Despite clear evidence of flagella-dependent adherence, the specificity of the ligands and mechanisms of binding are still debated. In this study, the molecular basis of Escherichia coli O157:H7 and Salmonella enterica serovar Typhimurium flagella binding to epithelial cell cultures was investigated. Flagella interactions with host cell...
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