Article
Analysis of the Exonic Single Nucleotide Polymorphism rs182428269 of the NRF2 Gene in Patients with Diabetic Foot Ulcer.
Archives of medical research - 1 Feb 2021
Teena Rajan, Dhamodharan Umapathy, Jayasuriya Ravichandran, Ali Daoud, Kesavan Rajesh, Ramkumar Kunka Mohanram
Abstract excerpt
BACKGROUND: The pivotal role of Nuclear factor erythroid-2-related factor 2 (NRF2) in redox homeostasis and wound healing has been well documented. However, the genetic mechanisms that regulate NRF2 in type 2 diabetes and diabetic foot ulcers remain unexplored. The present study investigated the association of single nucleotide polymorphism rs182428269 (-127 C/T) in subjects with type 2 diabetes and diabetic foot...
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