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Article

Therapeutic Strategies in Fragile X Syndrome: From Bench to Bedside and Back.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics - 1 Jul 2015

Gross Christina, Hoffmann Anne, Bassell Gary J, Berry-Kravis Elizabeth M

Abstract excerpt

Fragile X syndrome (FXS), an inherited intellectual disability often associated with autism, is caused by the loss of expression of the fragile X mental retardation protein. Tremendous progress in basic, preclinical, and translational clinical research has elucidated a variety of molecular-, cellular-, and system-level defects in FXS. This has led to the development of several promising therapeutic strategies,...

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Identifiers

PMID: 25986746
DOI: 10.1007/s13311-015-0355-9
PMCID: PMC4489963

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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