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Article

Comparison of Droplet Digital PCR versus qPCR Measurements on the International Scale for the Molecular Monitoring of Chronic Myeloid Leukemia Patients.

Molecular diagnosis & therapy - 1 Oct 2020

Cortés Alicia Arenas, Olmedillas Susana, Serrano-López Juana, Lainez-González Daniel, Castaño Tamara, Iñiguez Rodrigo, Lopez-Lorenzo José Luis, García Amanda, Atance Mireia, Sánchez Rocío Nieves Salgado, Lopez Carlos Blas, Arranz Mariano García, Sillero Pilar Llamas, Alonso-Dominguez Juan Manuel

Abstract excerpt

BACKGROUND: BCR-ABL1/ABL1 p210 measurement by quantitative polymerase chain reaction (qPCR) is used worldwide to monitor the molecular response in chronic myeloid leukemia (CML) patients. Droplet digital polymerase chain reaction (ddPCR) seems to show a greater sensitivity than qPCR, probably due to the high number of replicates analyzed in ddPCR for the comparison. Additionally, in a recently published...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32875515
DOI: 10.1007/s40291-020-00485-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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