Article
Digital PCR for BCR‐ABL1 Quantification in CML: Current Applications in Clinical Practice
24 Nov 2020
Abstract excerpt
Abstract Molecular monitoring of the BCR‐ABL1 transcript for patients with chronic phase chronic myeloid leukemia (CML) has become increasingly demanding. Real‐time quantitative PCR (qPCR) is the routinely used method, but has limitations in quantification accuracy due to its inherent technical variation. Treatment recommendations rely on specific BCR‐ABL1 values set at timed response milestones, making precise...
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