Article
The advantages and risks of ruxolitinib for the treatment of polycythemia vera.
Expert review of hematology - 1 Oct 2020
Colafigli Gioia, Scalzulli Emilia, Pepe Sara, Di Prima Alessio, Efficace Fabio, Martelli Maurizio, Foà Robin, Breccia Massimo
Abstract excerpt
INTRODUCTION: Polycythemia vera is a myeloproliferative neoplasm characterized by an increased red blood cell mass, risk of thromboembolic events, and of transformation into secondary myelofibrosis and acute leukemia. The goal of treatment is to reduce the risk of fatal cardiovascular events reducing the hematocrit level with phlebotomies and low-dose aspirin. In high-risk patients (age >60 years or previous...
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