Polycythaemia vera: molecular genetics, diagnostics and therapeutics.

doi:10.1111/vox.13069

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Article

Polycythaemia vera: molecular genetics, diagnostics and therapeutics.

Vox sanguinis - 1 Jul 2021

Putter Jeffrey S, Seghatchian Jerard

Abstract excerpt

Polycythaemia vera is one of several classical myeloproliferative neoplasms that may occur in a juvenile onset or late-onset adult forms. It is linked to specific genetic mutations that cause a deleterious elevation in the patient's red cell mass. The discourse on genetics includes an exposé on the molecular biology of the disease and how a shared JAK2 V617F mutation can co-exist among three distinct neoplasms....

Topics

Humans
Janus Kinase 2
Molecular Biology
Mutation
Polycythemia Vera
Thrombosis

Source

Open in PubMed

Identifiers

PMID: 33634867
DOI: 10.1111/vox.13069

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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