Article
Preparation, Supramolecular Aggregation and Immunological Activity of the Bona Fide Vaccine Adjuvant Sulfavant S.
Marine drugs - 29 Aug 2020
Manzo Emiliano, Fioretto Laura, Gallo Carmela, Ziaco Marcello, Nuzzo Genoveffa, D'Ippolito Giuliana, Borzacchiello Assunta, Fabozzi Antonio, De Palma Raffaele, Fontana Angelo
Abstract excerpt
In aqueous conditions, amphiphilic bioactive molecules are able to form self-assembled colloidal structures modifying their biological activity. This behavior is generally neglected in preclinical studies, despite its impact on pharmacological development. In this regard, a significative example is represented by a new class of amphiphilic marine-inspired vaccine adjuvants, collectively named Sulfavants, based on...
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