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Article

Structural basis of effector and operator recognition by the phenolic acid-responsive transcriptional regulator PadR.

Nucleic acids research - 15 Dec 2017

Park Sun Cheol, Kwak Yun Mi, Song Wan Seok, Hong Minsun, Yoon Sung-Il

Abstract excerpt

The PadR family is a large group of transcriptional regulators that function as environmental sensors. PadR negatively controls the expression of phenolic acid decarboxylase, which detoxifies harmful phenolic acids. To identify the mechanism by which PadR regulates phenolic acid-mediated gene expression, we performed structural and mutational studies of effector and operator recognition by Bacillus subtilis PadR....

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Identifiers

PMID: 29136175
DOI: 10.1093/nar/gkx1055
PMCID: PMC5728393

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