Article
B7-H4 and HHLA2, members of B7 family, are aberrantly expressed in EGFR mutated lung adenocarcinoma.
Pathology, research and practice - 1 Oct 2020
Chen Yan, Hu Ran, Li Xiaoyou, Shi Zhongyuan, Tian Hao, Feng Jifeng, Yu Shaorong
Abstract excerpt
BACKGROUND: In order to find new immune targets for lung cancer with different EGFR mutant status, we describe differential expression profiles of checkpoint molecules of the new discovery B7 family member to find new immune targets for lung cancer with different EGFR statuses. METHODS: We performed immunohistochemistry with antibodies of B7-H3, B7-H4, VISTA, B7-H6, HHLA2, IDO-1, PD-L1 and CD8 in lung...
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