Article
Developing and Using a Data Commons for Understanding the Molecular Characteristics of Germ Cell Tumors.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021
Ci Bo, Lin Shin-Yi, Yao Bo, Luo Danni, Xu Lin, Krailo Mark, Murray Matthew J, Amatruda James F, Frazier A Lindsay, Xie Yang
Abstract excerpt
Germ cell tumors (GCTs) are a rare disease, but they account for 15% of all malignancies diagnosed during adolescence. The biological mechanisms underpinning their development are only starting to be explored. Current GCT treatment may be associated with significant toxicity. Therefore, there is an urgent need to understand the molecular basis of GCT and identify biomarkers to tailor the therapy for individual...
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