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Structures of the Mononegavirales Polymerases

26 Aug 2020

Abstract excerpt

Mononegavirales , known as nonsegmented negative-sense (NNS) RNA viruses, are a class of pathogenic and sometimes deadly viruses that include rabies virus (RABV), human respiratory syncytial virus (HRSV), and Ebola virus (EBOV). Unfortunately, no effective vaccines and antiviral therapeutics against many Mononegavirales are currently available. Viral polymerases have been attractive and major antiviral...

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PMID: 32847861
DOI: 10.1128/jvi.00175-20

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