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Article

Gene polymorphisms (rs324957, rs324981) in NPSR1 are associated with increased risk of primary insomnia: A cross-sectional study.

Medicine - 21 Aug 2020

Xie Yuping, Zhao Yuan, Zhou Liya, Zhao Lijun, Wang Jinfeng, Ma Wei, Su Xiaoyan, Hui Peilin, Guo Bin, Liu Yu, Fan Jie, Zhang Shangli, Yang Jun, Chen Wenjuan, Wang Jing

Abstract excerpt

Neuropeptide S and neuropeptide S receptor (NPSR1) are associated with sleep regulation. Herein, the possible contribution of 6 polymorphisms in NPSR1 on the chromosome to primary insomnia (PI) and objective sleep phenotypes was investigated.The study included 157 patients with PI and 133 age- and sex-matched controls. All subjects were investigated by polysomnography for 3 consecutive nights. The genotyping of 6...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32846769
DOI: 10.1097/MD.0000000000021598
PMCID: PMC7447491

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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