Association between 5-hydroxytryptamine gene polymorphism rs140700 and primary insomnia in Chinese population.

doi:10.1111/imj.14813

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Article

Association between 5-hydroxytryptamine gene polymorphism rs140700 and primary insomnia in Chinese population.

Internal medicine journal - 1 May 2021

Hui Peilin, Yang Jun, Wang Jing, Zhao Lijun, Wang Xubin, Su Xiaoyan, Wang Jinfeng, Ma Wei, Fan Jie, Chen Wenjuan, Zhao Yuan, Guo Bin, Liu Yu, Zhang Shangli, Zheng Ning, Zhou Liyan, Xie Yuping

Abstract excerpt

BACKGROUND: Primary insomnia is a worldwide problem and it has a considerable negative impact on one's physical and mental health. Studies have shown that non-synonymous Single-nucleotide polymorphisms in 5-hydroxytryptamine (serotonin or 5-HT) are related to primary insomnia. Previous studies have shown that 5-HT polymorphism (rs140700) is related to depression, and insomnia is often accompanied by depression...

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PMID: 32149434
DOI: 10.1111/imj.14813

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