Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenetic effects of low-level sodium arsenite exposure on human liver HepaRG cells.

Archives of toxicology - 1 Dec 2020

Tryndyak Volodymyr P, Borowa-Mazgaj Barbara, Steward Colleen R, Beland Frederick A, Pogribny Igor P

Abstract excerpt

Chronic exposure to inorganic arsenic is associated with a variety of adverse health effects, including lung, bladder, kidney, and liver cancer. Several mechanisms have been proposed for arsenic-induced tumorigenesis; however, insufficient knowledge and many unanswered questions remain to explain the integrated molecular pathogenesis of arsenic carcinogenicity. In the present study, using non-tumorigenic human...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Liver Neoplasms
Share to Arsenites
Share to Cell Transformation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Claudins

Share to Epigenesis, Genetic

Share to Epithelial-Mesenchymal Transition

Share to Hepatocytes

Share to Histones

Source

Identifiers

PMID: 32844245
DOI: 10.1007/s00204-020-02872-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epigenetic effects of low-level sodium arsenite exposure on human liver HepaRG cells.PMID 32844245Read ↗

Effect of Long-Term Low-Dose Arsenic Exposure on DNA Methylation and Gene Expression in Human Liver CellsSemantic proximity Read ↗

Oncogenomic disruptions in arsenic-induced carcinogenesis.Semantic proximity Read ↗

Mechanistic Basis of Arsenic Induced Carcinogenesis: Differential miRNA ExpressionSemantic proximity Read ↗

An Emerging Role for Epigenetic Dysregulation in Arsenic Toxicity and CarcinogenesisSemantic proximity Read ↗

Environmental arsenic exposure: From genetic susceptibility to pathogenesis.Semantic proximity Read ↗

Role of genomic instability in arsenic-induced carcinogenicity. A review.Semantic proximity Read ↗

Arsenite exposure inhibits histone acetyltransferase p300 for attenuating H3K27ac at enhancers in low-dose exposed mouse embryonic fibroblast cellsSemantic proximity Read ↗

N6-methyladenosine mediates the cellular proliferation and apoptosis via microRNAs in arsenite-transformed cells.Semantic proximity Read ↗

Differentially Expressed mRNA Targets of Differentially Expressed miRNAs Predict Changes in the TP53 Axis and Carcinogenesis-Related Pathways in Human Keratinocytes Chronically Exposed to ArsenicSemantic proximity Read ↗

Arsenite alters global histone H3 methylationSemantic proximity Read ↗

Sodium Arsenite Induces Bronchial Epithelial Cell Cancer With Mitochondrial Dysfunction by Affecting Cell CycleSemantic proximity Read ↗

Recent Advances in Arsenic Research: Significance of Differential Susceptibility and Sustainable Strategies for Mitigation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.