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Article

N6-methyladenosine mediates the cellular proliferation and apoptosis via microRNAs in arsenite-transformed cells.

Toxicology letters - 1 Aug 2018

Gu Shiyan, Sun Donglei, Dai Huangmei, Zhang Zunzhen

Abstract excerpt

N6-methyladenosine (m6A) modification is implicated to play an important role in cellular biological processes, but its regulatory mechanisms in arsenite-induced carcinogenesis are largely unknown. Here, human bronchial epithelial (HBE) cells were chronically treated with 2.5 μM arsenite sodium (NaAsO2) for about 13 weeks and these cells were identified with malignant phenotype which was demonstrated by increased...

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Share to Adenosine
Share to Alpha-Ketoglutarate-Dependent Dioxygenase FTO

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Cell Transformation, Neoplastic

Share to Epithelial Cells

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Source

Identifiers

PMID: 29680375
DOI: 10.1016/j.toxlet.2018.04.018

Genes

METTL3
FTO
METTL14
WTAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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