Article
Reduced meiotic recombination in rhesus macaques and the origin of the human recombination landscape.
PloS one - 1 Jan 2020
Xue Cheng, Rustagi Navin, Liu Xiaoming, Raveendran Muthuswamy, Harris R Alan, Venkata Manjunath Gorentla, Rogers Jeffrey, Yu Fuli
Abstract excerpt
Characterizing meiotic recombination rates across the genomes of nonhuman primates is important for understanding the genetics of primate populations, performing genetic analyses of phenotypic variation and reconstructing the evolution of human recombination. Rhesus macaques (Macaca mulatta) are the most widely used nonhuman primates in biomedical research. We constructed a high-resolution genetic map of the...
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