Monacycliones G–K and ent-Gephyromycin A, Angucycline Derivatives from the Marine-Derived Streptomyces sp. HDN15129

Abstract excerpt

Six new angucycline derivatives, named monacycliones G–K ( 1 – 5 ) and ent -gephyromycin A ( 6 ), as well as three known ones ( 7 – 9 ) were discovered from the marine sediment-derived actinomycete Streptomyces sp. HDN15129 guided by Global Natural Products Social (GNPS) molecular networking. Structures including absolute configurations were elucidated by extensive NMR, MS, and ECD analyses. Among them,...

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