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Article

De novo design of an intercellular signaling toolbox for multi-channel cell-cell communication and biological computation.

Nature communications - 24 Aug 2020

Du Pei, Zhao Huiwei, Zhang Haoqian, Wang Ruisha, Huang Jianyi, Tian Ye, Luo Xudong, Luo Xunxun, Wang Min, Xiang Yanhui, Qian Long, Chen Yihua, Tao Yong, Lou Chunbo

Abstract excerpt

Intercellular signaling is indispensable for single cells to form complex biological structures, such as biofilms, tissues and organs. The genetic tools available for engineering intercellular signaling, however, are quite limited. Here we exploit the chemical diversity of biological small molecules to de novo design a genetic toolbox for high-performance, multi-channel cell-cell communications and biological...

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PMID: 32839450
DOI: 10.1038/s41467-020-17993-w
PMCID: PMC7445162

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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