Article
Metabolomic analysis coupled with extreme phenotype sampling identified that lysophosphatidylcholines are associated with multisite musculoskeletal pain.
Pain - 1 Feb 2021
Liu Ming, Xie Zikun, Costello Christie A, Zhang Weidong, Chen Liujun, Qi Dake, Furey Andrew, Randell Edward W, Rahman Proton, Zhai Guangju
Abstract excerpt
ABSTRACT: Musculoskeletal pain often occurs simultaneously at multiple anatomical sites. The aim of the study was to identify metabolic biomarkers for multisite musculoskeletal pain (MSMP) by metabolomics with an extreme phenotype sampling strategy. The study participants (n = 610) were derived from the Newfoundland Osteoarthritis Study. Musculoskeletal pain was assessed using a self-reported pain questionnaire...
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