Metabolic-inflammatory phenotypes, osteoarthritis, and lower-extremity functional limitation in US adults: a NHANES 2007-2018 study.

doi:10.1007/s10067-026-08312-7

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Metabolic-inflammatory phenotypes, osteoarthritis, and lower-extremity functional limitation in US adults: a NHANES 2007-2018 study.

Clinical rheumatology - 1 Sept 2026

Yang Haotian, Yu Kuike, Chen Yu, Sun Zhenlin, Wang Wei, Tao Ran

Abstract excerpt

INTRODUCTION: To identify metabolic-inflammatory profiles in US adults and assess their cross-sectional associations with self-reported osteoarthritis (OA) and lower-extremity functional limitation. METHODS: We analyzed six National Health and Nutrition Examination Survey cycles from 2007-2008 to 2017-2018. Latent class analysis used body mass index, waist circumference, systolic blood pressure, diabetes, and...

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PMID: 42541683
DOI: 10.1007/s10067-026-08312-7

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