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ADVANTAGE: Advanced discovery of visceral analgesics by neuroimmune targets and the genetics of extreme human phenotype, a study protocol.

PloS one - 1 Jan 2026

Alban-Paccha Marco Vinicio, Shenker Nicholas, Teran-Perez Jimena, Horne Andrew W, Malliaras George G, Woods Christopher Geoffrey

Abstract excerpt

Chronic visceral pain affects over 20% of adults globally but remains poorly understood, significantly impacting quality of life and healthcare costs. Limited understanding and diagnostic misconceptions hinder effective management, particularly during acute pain flares. This study aims to clarify underlying mechanisms and improve clinical management by combining detailed phenotyping, genetic analysis,...

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PMID: 42166469
DOI: 10.1371/journal.pone.0350169
PMCID: PMC13193507

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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