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Article

Machine Learning and Pathway Analysis-Based Discovery of Metabolomic Markers Relating to Chronic Pain Phenotypes.

International journal of molecular sciences - 3 May 2022

Miettinen Teemu, Nieminen Anni I, Mäntyselkä Pekka, Kalso Eija, Lötsch Jörn

Abstract excerpt

Recent scientific evidence suggests that chronic pain phenotypes are reflected in metabolomic changes. However, problems associated with chronic pain, such as sleep disorders or obesity, may complicate the metabolome pattern. Such a complex phenotype was investigated to identify common metabolomics markers at the interface of persistent pain, sleep, and obesity in 71 men and 122 women undergoing tertiary pain...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35563473
DOI: 10.3390/ijms23095085
PMCID: PMC9099732

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