Article
Pharmacogenetics of antipsychotics in adolescents with acute psychotic episode during first 14 days after admission: effectiveness and safety evaluation.
Drug metabolism and personalized therapy - 24 Aug 2020
Ivashchenko Dmitriy V, Khoang Sofi Z, Makhmudova Bakhu V, Buromskaya Nina I, Shimanov Pavel V, Deitch Roman V, Akmalova Kristina A, Shuev Grigoriy N, Dorina Irina V, Nastovich Marina I, Shagovenko Eugenia N, Grishina Elena A, Savchenko Lyudmila M, Shevchenko Yuriy S, Sychev Dmitriy A
Abstract excerpt
OBJECTIVES: Prediction of the antipsychotic's effectiveness is a relevant topic in the field of personalized medicine. METHODS: The research design of this study is a prospective observation with posthoc analysis of associations of genetic polymorphisms with safety parameters and effectiveness of antipsychotic therapy. We observed 53 adolescents with an acute psychotic episode which were prescribed antipsychotics...
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