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Increased PIEZO1 Expression Is Associated with Worse Clinical Outcomes in Hormone-Receptor-Negative Breast Cancer Patients

6 Feb 2024

Abstract excerpt

PIEZO1 plays a crucial role in the human body as a mechanosensory ion channel. It has been demonstrated that PIEZO1 is important in tissue development and regulating many essential physiological processes. Studies have suggested that the PIEZO1 ion channel plays a role in invasion and progression in cancer; elevated levels of PIEZO1 have been correlated with increased migration in breast cancer cells,...

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PMID: 38398074
DOI: 10.3390/cancers16040683

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Increased PIEZO1 Expression Is Associated with Worse Clinical Outcomes in Hormone-Receptor-Negative Breast Cancer PatientsPMID 38398074Read ↗

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Identification of PIEZO1 as a potential prognostic marker in gliomasSemantic proximity Read ↗

miR-10b-5p-mediated upregulation of PIEZO1 predicts poor prognosis and links to purine metabolism in breast cancerSemantic proximity Read ↗

PIEZO2 expression is an independent biomarker prognostic for gastric cancer and represents a potential therapeutic targetSemantic proximity Read ↗

Comprehensive analysis of mRNA expression of Piezo1 and Piezo2 in tumor samples and their prognostic implications in gastric cancerSemantic proximity Read ↗

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