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Article

Generation of foxn1/Casper Mutant Zebrafish for Allograft and Xenograft of Normal and Malignant Cells.

Stem cell reports - 8 Sept 2020

Lv Peng, Ma Dongyuan, Gao Shuai, Zhang Yifan, Bae Young-Ki, Liang Guixian, Gao Suwei, Choi Jung-Hwa, Kim Cheol-Hee, Wang Lu, Liu Feng

Abstract excerpt

Cell transplantation into immunodeficient recipients is a widely used approach to study stem cell and cancer biology; however, studying cell states post transplantation in vivo is inconvenient in mammals. Here, we generated a foxn1/Casper mutant zebrafish that is transparent and exhibits T cell deficiency. By employing the line for hematopoietic stem cell (HSC) transplantation (HSCT), we could achieve...

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Identifiers

PMID: 32822590
DOI: 10.1016/j.stemcr.2020.07.020
PMCID: PMC7486299

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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