Article

Stagewise identification of significantly mutated and dysregulated gene clusters in major molecular classes of breast invasive carcinoma

2020-05-31

Abstract excerpt

Breast invasive carcinoma (BRCA) is most malignant and leading cause of death in women. The efforts are ongoing for improvement in early detection, prevention and treatment. Therefore, identification of biomarkers/candidate genes has become very important. The current work includes comprehensive analysis of RNA-sequencing data of 1097 BRCA samples and 114 normal adjacent tissues to identify dysregulated genes in m...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 72674225-64af-51e8-965d-f487d663f02f
DOI: 10.1101/2020.05.30.125260

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Stagewise identification of significantly mutated and dysregulated gene clusters in major molecular classes of breast invasive carcinomaDOI 10.1101/2020.05.30.125260Read

Differentially Expressed Genes and Key Pathways in Triple Negative Breast Cancers: A Bioinformatics AnalysisSemantic proximity Read

Identification and validation of molecular subtypes and a 9-gene risk model for breast cancer.Semantic proximity Read

Secondary Transcriptomic Analysis of Triple Negative Breast Cancer Reveals Reliable Universal and Subtype-Specific BiomarkersSemantic proximity Read

Integrated transcriptomic meta-analysis provides novel insights into breast cancer molecular subtypesSemantic proximity Read

Insilico-based identification of survival-associated lncRNAs, mRNAs and, miRNAs in breast cancerSemantic proximity Read

Genomic and Transcriptomic Landscape of Triple-Negative Breast Cancers: Subtypes and Treatment StrategiesSemantic proximity Read

Whole exome sequencing of breast cancer (TNBC) cases from India: association of MSH6 and BRIP1 variants with TNBC risk and oxidative DNA damage.Semantic proximity Read

Integrated Transcriptome and Pathway Analyses Revealed Multiple Activated Pathways in Breast CancerSemantic proximity Read

Radiogenomic analysis of the correlation between clinical, ultrasound characteristics and immune-related genes in breast cancerSemantic proximity Read

Investigation of the Genomic and Transcriptomic Variations Underlying Tamoxifen Resistance in Breast CancerSemantic proximity Read

Study of APOBEC3B focused breast cancer pathways and the clinical relevanceSemantic proximity Read