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Article

Identification and validation of seven new loci showing differential DNA methylation related to serum lipid profile: an epigenome-wide approach. The REGICOR study.

Human molecular genetics - 15 Oct 2016

Sayols-Baixeras S, Subirana I, Lluis-Ganella C, Civeira F, Roquer J, Do A N, Absher D, Cenarro A, Muñoz D, Soriano-Tárraga C, Jiménez-Conde J, Ordovas J M, Senti M, Aslibekyan S, Marrugat J, Arnett D K, Elosua R

Abstract excerpt

Lipid traits (total, low-density and high-density lipoprotein cholesterol, and triglycerides) are risk factors for cardiovascular disease. DNA methylation is not only an inherited but also modifiable epigenetic mark that has been related to cardiovascular risk factors. Our aim was to identify loci showing differential DNA methylation related to serum lipid levels. Blood DNA methylation was assessed using the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28173150
DOI: 10.1093/hmg/ddw285
PMCID: PMC6284258

Genes

PHOSPHO1
ABCG1
SYNGAP1
TXNIP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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