Article
Extreme Phenotype Approach Suggests Taste Transduction Pathway for Carotid Plaque in a Multi-Ethnic Cohort.
Stroke - 1 Sept 2020
Dueker Nicole D, Doliner Brett, Gardener Hannah, Dong Chuanhui, Beecham Ashley, Della-Morte David, Sacco Ralph L, Blanton Susan H, Wang Liyong, Rundek Tatjana
Abstract excerpt
BACKGROUND AND PURPOSE: Carotid plaque is a heritable trait and a strong predictor of vascular events. Several loci have been identified for carotid plaque, however, studies in minority populations are lacking. Within a multi-ethnic cohort, we have identified individuals with extreme total carotid plaque area (TCPA), that is, higher or lower TCPA than expected based on traditional vascular risk factors (age, sex,...
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