Article
Large-scale prion protein genotyping in Canadian caribou populations and potential impact on chronic wasting disease susceptibility.
Molecular ecology - 1 Oct 2020
Arifin Maria Immaculata, Staskevicius Antanas, Shim Su Yeon, Huang Yuan-Hung, Fenton Heather, McLoughlin Philip D, Mitchell Gordon, Cullingham Catherine I, Gilch Sabine
Abstract excerpt
Polymorphisms within the prion protein gene (Prnp) are an intrinsic factor that can modulate chronic wasting disease (CWD) pathogenesis in cervids. Although wild European reindeer (Rangifer tarandus tarandus) were infected with CWD, as yet there have been no reports of the disease in North American caribou (R. tarandus spp.). Previous Prnp genotyping studies on approximately 200 caribou revealed single nucleotide...
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