Article
Familial inclusion body myositis: a report on two Japanese sisters.
Internal medicine (Tokyo, Japan) - 1 Oct 2003
Tateyama Maki, Saito Naohiro, Fujihara Kazuo, Shiga Yusei, Takeda Atsushi, Narikawa Koichi, Hasegawa Takafumi, Taguchi Yuzuru, Sakuma Ryo, Onodera Yoshiaki, Ohnuma Ayumu, Tobita Muneshige, Itoyama Yasuto
Abstract excerpt
Familial occurrence of inclusion body myositis is extremely rare, and only a few cases in Western countries have been reported. In these reports, a strong association of this disease with DR3 (DRB1*0301/0302) and the efficacy of immunosuppressants suggested that an immune pathomechanism is involved in the disease. We, for the first time, report two Japanese sisters who suffered myopathy clinicopathologically...
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