Article
Genome-Wide Association Study of Brain Alzheimer's Disease-Related Metabolic Decline as Measured by [18F] FDG-PET Imaging.
Journal of Alzheimer's disease : JAD - 1 Jan 2020
Wang Rong-Ze, Yang Yu-Xiang, Li Hong-Qi, Shen Xue-Ning, Chen Shi-Dong, Dong Qiang, Wang Yi, Yu Jin-Tai
Abstract excerpt
BACKGROUND: Hypometabolism detected by fluorodeoxyglucose F18 positron emission tomography ([18F] FDG PET) is an early neuropathologic changes in Alzheimer's disease (AD) and provides important pathologic staging information. OBJECTIVE: This study aimed to discover genetic interactions that regulate longitudinal glucose metabolic decline in AD-related brain regions. METHODS: A total of 586 non-Hispanic white...
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