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Article

Antithrombin Deficiency in Trauma and Surgical Critical Care.

The Journal of surgical research - 1 Dec 2020

Ehrhardt John D, Boneva Dessy, McKenney Mark, Elkbuli Adel

Abstract excerpt

Antithrombin deficiency (ATD) was described in 1965 by Olav Egeberg as the first known inherited form of thrombophilia. Today, it is understood that ATDs can be congenital or acquired, leading to qualitative, quantitative, or mixed abnormalities in antithrombin (AT). All ATDs ultimately hinder AT's ability to serve as an endogenous anticoagulant and antiinflammatory agent. As a result, ATD patients possess higher...

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PMID: 32799002
DOI: 10.1016/j.jss.2020.07.010

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