Article
11-Oxygenated C19 Steroids Do Not Distinguish the Hyperandrogenic Phenotype of PCOS Daughters from Girls with Obesity.
The Journal of clinical endocrinology and metabolism - 1 Nov 2020
Torchen Laura C, Sisk Ryan, Legro Richard S, Turcu Adina F, Auchus Richard J, Dunaif Andrea
Abstract excerpt
CONTEXT: Hyperandrogenemia (HA) is a consistent reproductive phenotype in women with polycystic ovary syndrome (PCOS) and their relatives. Increased testosterone levels are present in premenarchal daughters of affected women (PCOS-d). Obese girls (OB-g) without a family history of PCOS also have peripubertal HA. The sources and significance of HA in these groups remains unknown. OBJECTIVE: 11-oxygenated 19-carbon...
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