Article
DHEA, DHEAS and PCOS.
The Journal of steroid biochemistry and molecular biology - 1 Jan 2015
Goodarzi Mark O, Carmina Enrico, Azziz Ricardo
Abstract excerpt
Approximately 20-30% of PCOS women demonstrate excess adrenal precursor androgen (APA) production, primarily using DHEAS as a marker of APA in general and more specifically DHEA, synthesis. The role of APA excess in determining or causing PCOS is unclear, although observations in patients with inherited APA excess (e.g., patients with 21-hydroxylase deficient congenital classic or non-classic adrenal hyperplasia)...
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