Article
Detection of PIK3CA E545A mutation in circulating tumor DNA of a patient affected by uterine carcinosarcoma.
Anti-cancer drugs - 1 Sept 2020
Fantappiè Giulia, Malentacchi Francesca, Turrini Irene, Sorbi Flavia, Castiglione Francesca, Vergoni Federica, Ammatuna Carlo, Antonuzzo Lorenzo, Fambrini Massimiliano, Noci Ivo, Pillozzi Serena
Abstract excerpt
Uterine carcinosarcomas are biphasic neoplasms consisting of mixed epithelial and mesenchymal elements, representing less than 5% of all uterine malignancies. Carcinosarcomas are rare, although the most common cause of uterine cancer-specific death. Few information is available on the pathogenesis, and molecular characterization is poorly investigated. Consequently, the treatment has not changed over the last...
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