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Article

Tumor-related mutations in cell-free DNA in pre-operative plasma as a prognostic indicator of recurrence in endometrial cancer.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Sept 2020

Shintani Daisuke, Hihara Taro, Ogasawara Aiko, Sato Sho, Yabuno Akira, Tai Kenji, Fujiwara Keiichi, Watanabe Keisuke, Hasegawa Kosei

Abstract excerpt

OBJECTIVES: Circulating tumor DNA (ctDNA) has potential as a basis for understanding the molecular features of a tumor non-invasively and for use as a diagnostic, prognostic, and disease-monitoring marker. The aim of this study was to evaluate the clinical roles of ctDNA in patients with endometrial cancer. METHODS: Since PIK3CA and KRAS are among the most common mutated genes in endometrial cancer, somatic...

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Cancer Genomics and Diagnostics
Circulating Tumor DNA
Endometrial and Cervical Cancer Treatments
Endometrial Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasm Recurrence, Local

Prostate Cancer Treatment and Research

Survival Analysis

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PMID: 32699017
DOI: 10.1136/ijgc-2019-001053

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