Article
[Influence of methylenetetrahydrofolate reductase gene polymorphisms on antidepressant response].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Feb 2013
Sun Xiao-yan, Zhang Zhi-jun, Shi Yan-yan, Xu Zhi, Pu Meng-jia, Geng Lei-yu
Abstract excerpt
OBJECTIVE: To assess the influence of polymorphisms of methylenetetrahydrofolate reductase (MTHFR) gene on response to antidepressant treatment. METHODS: Two hundred and eight one Chinese Han patients have received single antidepressant drugs for at least 6 weeks, among whom 275 were followed up for 8 weeks. Hamilton depression scale 17 (HAMD-17) was used to evaluate the severity of depressive symptoms and...
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