Current Understanding of the Genetics of Intervertebral Disc Degeneration

doi:10.3389/fvets.2020.00431

Article

Current Understanding of the Genetics of Intervertebral Disc Degeneration

24 Jul 2020

Abstract excerpt

Premature degeneration of the intervertebral disc and its association with specific chondrodystrophic dog breeds has been recognized for over a century. Several lines of evidence including disease breed predisposition, studies suggesting heritability of premature intervertebral disc degeneration (IVDD) and association of a dog chromosome 12 (CFA 12) locus with intervertebral disc calcification have strongly...

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