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Article

The molecular landscape and associated clinical experience in infant medulloblastoma: prognostic significance of second‐generation subtypes

11 Aug 2020

Abstract excerpt

Aims Biomarker‐driven therapies have not been developed for infant medulloblastoma (iMB). We sought to robustly sub‐classify iMB, and proffer strategies for personalized, risk‐adapted therapies. Methods We characterized the iMB molecular landscape, including second‐generation subtyping, and the associated retrospective clinical experience, using large independent discovery/validation cohorts (n = 387). Results...

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PMID: 32779246
DOI: 10.1111/nan.12656

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