Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic testing in Poland and Ukraine: should comprehensive germline testing of BRCA1 and BRCA2 be recommended for women with breast and ovarian cancer?

Genetics research - 10 Aug 2020

Nguyen-Dumont Tu, Karpinski Pawel, Sasiadek Maria M, Akopyan Hayane, Steen Jason A, Theys Derrick, Hammet Fleur, Tsimiklis Helen, Park Daniel J, Pope Bernard J, Slezak Ryszard, Stembalska Agnieszka, Pesz Karolina, Kitsera Nataliya, Siekierzynska Aleksandra, Southey Melissa C, Myszka Aleksander

Abstract excerpt

PURPOSE: To characterize the spectrum of BRCA1 and BRCA2 pathogenic germline variants in women from south-west Poland and west Ukraine affected with breast or ovarian cancer. Testing in women at high risk of breast and ovarian cancer in these regions is currently mainly limited to founder mutations. METHODS: Unrelated women affected with breast and/or ovarian cancer from Poland (n = 337) and Ukraine (n = 123)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BRCA1 Protein
Share to BRCA2 Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Breast Neoplasms

Share to Germ-Line Mutation

Share to High-Throughput Nucleotide Sequencing

Share to Ovarian Neoplasms

Share to Poland

Share to Ukraine

Source

Open in PubMed Open full text

Identifiers

PMID: 32772980
DOI: 10.1017/S0016672320000075
PMCID: PMC7443769

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic testing in Poland and Ukraine: should comprehensive germline testing of BRCA1 and BRCA2 be recommended for women with breast and ovarian cancer?PMID 32772980Read ↗

BRCA1 and BRCA2 mutation analysis in breast-ovarian cancer families from northeastern PolandSemantic proximity Read ↗

Frequency of BRCA1 and BRCA2 causative founder variants in ovarian cancer patients in South-East PolandSemantic proximity Read ↗

A high proportion of founder BRCA1 mutations in Polish breast cancer families.Semantic proximity Read ↗

AGO Austria recommendations for genetic testing of patients with ovarian cancer.Semantic proximity Read ↗

Frequency and spectrum of founder and non-founder BRCA1 and BRCA2 mutations in a large series of Russian breast cancer and ovarian cancer patients.Semantic proximity Read ↗

Clinicopathological features of breast cancer in Ukrainian women with BRCA1 c.181T>G (p.Cys61Gly) variant: a case series.Semantic proximity Read ↗

Contribution of BRCA1 5382insC mutation to triplene-gative and luminal types of breast cancer in Ukraine.Semantic proximity Read ↗

Targeted massively parallel sequencing characterises the mutation spectrum of PALB2 in breast and ovarian cancer cases from Poland and Ukraine.Semantic proximity Read ↗

Prevalence of two BRCA1 mutations, 5382insC and 300T > G, in ovarian cancer patients from Ukraine.Semantic proximity Read ↗

Spectrum and characterisation of BRCA1 and BRCA2 deleterious mutations in high-risk Czech patients with breast and/or ovarian cancer.Semantic proximity Read ↗

Prevalence of recurrent and non-recurrent BRCA1 and BRCA2 pathogenic variants in Polish breast cancer patients: insights from a regional genetic testing cohort from Lower Silesia.Semantic proximity Read ↗

New Germinal Mutation of BRCA1 gene (c.829_832delAATA) in a Polish Patient with Breast/Ovarian CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.