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Article

Comparison of Large, Medium, and Small Solid Tumor Gene Panels for Detection of Clinically Actionable Mutations in Cancer.

Targeted oncology - 1 Aug 2020

Vail Eric, Song Jianbo, Xu Jing, Frye Joseph S, Kim Jong Taek, Pao Andy, Schreck Rhona, Aguiluz Angela S, Zhang Wenjuan, Alkan Serhan, Mita Alain, Mita Monica, Figlin Robert A, Engman David M, Lopategui Jean R

Abstract excerpt

BACKGROUND: Next-generation sequencing of gene panels has supplanted single-gene testing for cancer molecular diagnostics in many laboratories. Considerations for the optimal number of genes to assess in a panel depend on the purpose of the testing. OBJECTIVE: To address the optimal size for the identification of clinically actionable variants in different-sized solid tumor sequencing panels. PATIENTS AND...

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PMID: 32770442
DOI: 10.1007/s11523-020-00743-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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