Article
Mutation Yield of a 34-Gene Solid Tumor Panel in Community-Based Tumor Samples.
Molecular diagnosis & therapy - 1 Jun 2016
Sanders Heather, Qu Kevin, Li Hairong, Ma Lin, Barlan Cindy, Zhang Xi, Prentice James, Wolfson David, Crossley Beryl, Sferruzza Anthony, Sninsky John, Ross David, Grupe Andrew, Catanese Joseph, Hantash Feras, Waldman Frederic
Abstract excerpt
BACKGROUND: Several targeted therapies have been approved for treatment of solid tumors. Identification of gene mutations that indicate response to these therapies is rapidly progressing. A 34-gene next-generation sequencing (NGS) panel, developed and validated by us, was evaluated to detect additional mutations in community-based cancer specimens initially sent to our reference laboratory for routine molecular...
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