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Article

Prognostic Significance of Circulating Tumor Cells with Mesenchymal Phenotypes in Patients with Gastric Cancer: A Prospective Study.

Annals of surgical oncology - 1 Feb 2021

Ishiguro Yui, Sakihama Hideyasu, Yoshida Tadashi, Ichikawa Nobuki, Homma Shigenori, Fukai Moto, Kawamura Hideki, Takahashi Norihiko, Taketomi Akinobu

Abstract excerpt

BACKGROUND: Circulating tumor cells (CTCs) have been shown to be heterogeneous. Focusing on the epithelial-mesenchymal transition and perioperative kinetics, we evaluated CTCs with mesenchymal phenotypes as a potential prognostic biomarker for patients with gastric cancer. METHODS: Peripheral blood was collected from 54 patients with gastric cancer before surgery and at 1 week and 1 month after surgery. CTCs were...

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PMID: 32770296
DOI: 10.1245/s10434-020-08827-6

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